Medicinal Mushrooms- Its Properties And Unexplored Potential As Nutraceutical Supplement.

Mushrooms have been consumed since earliest history. From the Greeks to the Chinese, mushroom has made room for itself in all cultures. Ancient Greeks believed that mushrooms provided strength for warriors in battle and the Romans perceived it as “Food of God.” For centuries, Chinese culture has treasured mushrooms as a healthy food, an “elixir of life.” They have been part of human culture for thousands of years owing to its nutritional, medicinal and value-added benefits. 

More than 2,000 species of mushrooms exist in nature but only around 25 are widely accepted as food and few are commercially cultivated. Mushrooms are considered as a delicacy with high nutritional and functional value, and they are also accepted as nutraceutical foods. They are of considerable interest because of their medicinal properties, and economic significance. Let’s understand in depth the magical significance of medicinal mushroom Cordyceps in our lives. 

About Cordyceps

It was first recorded  by a Chinese habitant, Wang Ang in 1694 and the Italian scholar Saccardo who named the Cordyceps officially as Cordyceps Sinensis in 1858, that nomenclature has been used ever since. The name Cordyceps has been derived from two Latin words, i.e., cord and ceps meaning club and head, respectively. Of the more than 400 species of Cordyceps discovered, two have become the focus of health research, Cordyceps Sinensis and Cordyceps Militaris.For centuries supplements and products containing Cordyceps, the  most valuable medicinal mushroom are helping in maintaining good health. 

Both species contain concentrations of 2 compounds-adenosine and cordycepin. Cordyceps Sinensis contains more adenosine than Cordyceps Militaris, but no cordycepin (a compound known for various nutraceutical and therapeutic potential with numerous health benefits).  Cordyceps Militaris contains cordycepin and costs a fraction of Cordyceps Sinensis.  Incidentally, since July 2020, world’s costliest fungus (sold in International markets for upwards of Rs 20 lakh per kg) is in the red list of International Union for Conservation of Nature (IUCN) due to over harvesting and banned from collecting & sale of Cordyceps Sinensis is to conserve, so that it remains in the wild. 

Cordyceps Militaris, on the other hand, is grown in labs using mycelia extracts planted on grain. Although it presents many of the same benefits as Cordyceps Sinensis and more in some cases, biotechnology helps  to produce it under sterile & controlled environment  and is economical to purchase. Cordyceps Militaris is a commercially cultivated species of Cordyceps that is grown in artificial environment. It is said to have even higher concentrations of medical compounds than its wild counterparts.

Benefits Of Cordyceps Mushrooms

Cordyceps mushrooms are commonly recommended for a wide range of medical conditions and wellness benefits that include: 

  • Promote increased endurance
  • Has immunomodulatory, anti-oxidative, anti-inflammatory, and anti-tumor properties
  • Help manage Type 2 diabetes
  • Support heart health
  • Improve sleep cycles
  • Contains “anti-aging” benefits, including increased vigour and longevity and improved sexual function

Enhance Athletic Activity

Adenosine triphosphate – commonly known as “ATP” – is a molecule found within our body. The primary function of ATP is to deliver energy to all of our body cells. This includes those that make up our muscles. Cordyceps  increases our body’s production of ATP. This means it is especially beneficial before exercise or during physical activity, as it helps to increase endurance and prevent fatigue. It also increases lung capacity, thus, an excellent benefit for almost any type of exercise or physical activity. 

Cordyceps is not only recommended prior to a workout but is a beneficial post-workout supplement, as well. The anti-inflammatory effects can help reduce swelling and muscle fatigue. Plus, it’s energy-boosting properties can help fight a post-workout crash so that you can continue your day with less down-time. Cordyceps also supports exercise tolerance and endurance even in as little as one week of regular use. 

Immunomodulatory Effects

The immune system protects human beings from infection with layered defences of increasing specificity. Many chronic conditions and autoimmune disorders are related to an overactive or hypersensitive immune system. An under-active or overly-fatigued immune system is also problematic, as it may not protect us from infections, a vital part of human wellness. Substances that help regulate the immune system can help us to maintain wellness even in the most precarious environments. The adaptive immune response is activated by the response of the innate immune system. Cordyceps Militaris is a bidirectional modulator with both potentiating and suppressive effects on the immune system through regulating innate and adaptive immunity.

Antioxidant, Anti-Inflammatory And Anti-Tumor Benefits

One of the primary components of Cordyceps  is cordycepin, as you know by this time. This substance has strong anti-oxidant, anti-inflammatory, and anti-cancer benefits.

Antioxidants

Oxidative effects are responsible for a range of negative health consequences. This includes damage to cell membranes and lipoproteins. Oxidative effects are often a typical part of aging. This is due to the body being less able to defend against the damage of free radicals. Free radicals are substances naturally produced by the body in response to environmental stressors, as well as a by-product of metabolic processes. Antioxidant substances help to protect against this type of damage. Consequently it helps the body to avoid these harmful effects and Cordyceps have potent antioxidant properties.

Anti-Inflammatory & Anti-Tumor

Inflammation is a normal, healthy biological response to cell or tissue injury caused by physical or chemical stimuli, or by bacteria, viruses, or toxins. This response helps to protect the body and facilitate healing and recovery. However, the same substances that induce an inflammatory response within the body can sometimes become unregulated. This leads to prolonged inflammation that is commonly associated with chronic illness and even cancer. Helping the body to moderate and reduce this inflammatory response is a critical part of both modern and traditional medicine. This is due to effective anti-inflammatories being one of the most sought-after and recommended therapies for a wide range of symptoms and conditions. Cordyceps helps to reduce this inflammatory response by inhibiting pro-inflammatory cytokines. It acts as an effective adjunctive therapy in the treatment of certain types of cancer. Cordycepin inhibits tumor growth, as well as helps to reverse some of the negative effects of chemotherapy. 

Helps Manage Type 2 Diabetes

Cordycepin helps to  treat Type 2 Diabetes, by  lowering  blood sugar levels, as well as  helps  regulate glucose metabolism. Additionally, cordycepin helps  to protect against kidney and spleen injury, a common concern among patients with diabetes. 

Supports Heart Health

Cordyceps has long been recommended for its protective effects on many organs, including the heart, liver, lungs, and kidneys. The cardiovascular effects of Cordyceps are probably one of the most highly touted benefits. Cordyceps benefits heart health through a variety of possible ways, by:

  • lowering blood pressure via direct dilation of blood vessels,
  • improving blood circulation in both the heart and brain 
  • help rectify abnormal heart rhythms
  • Increase cardiac output when utilized in addition to conventional treatments for chronic heart failure
  • decrease blood viscosity and fibrinogen levels which helps  to prevent heart attack. 

Improves Sleep Cycle

It is also proven to help to reset circadian rhythms deeper and offer better-quality sleep. Circadian Rhythm means, the natural cycle of physical, mental, and behaviour changes that the body goes through in a 24-hour cycle, such as the sleep-wake cycle, the body-temperature cycle, and the cycles in which a number of hormones are secreted.

Anti-Aging Benefits & Sexual Health

Cordyceps is often promoted as beneficial for its “anti-aging” properties, especially in ancient literature. These effects are usually described as “increased vigor” and “longevity”. While more recent research explains how Cordyceps work to protect against organ damage, promote energy, and help to fight fatigue, Cordyceps also  helpful for improving sexual health. Cordyceps has been shown to increase libido and restore reproductive function. Both of these effects are related to the enhancement of testosterone. As a decrease in sexual vitality is often associated with aging, the ability to potentially reverse these changes is nevertheless exciting and appreciated by many.

Understanding The Inside Story Of Ingredients-

To enhance the wellness of Cordyceps Militaris, formulating in right proposition with other organic super-food and adaptogenic mushrooms, such as Bee Pollen and Trametes Versicolor (Turkey Tail) mushrooms add value. Be assured, Vanya takes pride to offer these unique combinations that’s unmatched by other Brands, both in India & Overseas. 

The quality that goes into the raw materials is the core of every product – it decides the final quality of the product. We grow virgin Cordyceps Militaris in-house, cultivated under ideal growing conditions in our state of the art tissue culture facility and Bee Pollen grains &  Turkey Tail  are sourced from Garhwal region of Himalayan range and blended to optimize the health benefits to the consumers. All this goodness is captured uniquely in vegetarian capsules, made out of tasteless & vegan appropriate natural cellulose fibre, which breaks down instantly and acts faster as it gets into the bloodstream, almost immediately. 

Benefits Of Bee Pollen

Bee pollen is a food that comes from the pollen of flowers. It is collected by the bees and mixed with nectar and salivary substances to obtain the shape of a small granule. The bees carry it on their hind legs and take it back to the hive where the beekeeper collects it by means of a pollen trap. Pollen contains 19 of the 21 essential amino acids in nature, which is why it is attributed with unique properties as a nutrient. Each grain contains 100,000 to 5,000,000 of pollen granules. Nutritional profile of bee pollen has more than 250 active substances including proteins, carbs, lipids, fatty acids, vitamins, minerals, enzymes and antioxidants. Also, due to its high antioxidant content, it protects from free radicals and chronic diseases such as cancer and type 2 diabetes.

Additionally, it lowers blood cholesterol levels, especially “bad” LDL cholesterol and blood lipids and also decreases the risk of heart diseases. It also boosts liver function and protects from toxic substances. It also avoids illness by boosting immunity and killing bacteria. Reduces the activation of mast cells and lowers the severity and onset of allergies. It offers an added advantage of reducing stretch marks for women and is also helpful in burning belly fat. One of the significant benefits-it improves nutrient utilization, metabolism and longevity.

Benefits Of Trametes Versicolor (Turkey Tail)

Trametes Versicolor gets its name due to the mushroom’s striking variety of colours and resemblance to a turkey tail structure. The words turkey tail mushroom and anti-carcinogenic can often be found in the same sentence with its relevance with monocytes, white blood cells that fight infection. PSP (polysaccharide peptide) is a property that protects against bacteria. Both PSP and PSK (polysaccharide krestin) are used in conjunction with other cancer-fighting efforts. But turkey tails produce this naturally and don’t attack healthy cells. Over two-third of cancer-related deaths could be prevented or reduced by modifying our diet with mushrooms, as they contain antioxidants. People use turkey tail mushrooms to improve response to cancer medicines and chemotherapy & radiation. It is also full of antioxidants which help reduce the damage that is caused by oxidative stress. Additionally, probiotics are essential to a healthy gut biome and the turkey tail mushroom also takes care of that issue. 

Production Facility With Cutting-Edge Technology

Vanya’s  tissue culture laboratory for Cordyceps Militaris is equipped with state-of-the-art machinery & equipment with automation by microprocessor based PID controller, sequential timer, microclimatic controller, photoperiodic timer and pressure chamber, that precisely controls and monitors both extrinsic and intrinsic factors.  Cordyceps Militaris is cultivated under aseptic conditions by micro propagation.

Extrinsic Factors:

  • Temperature 
  • Humidity 
  • CO2 
  • Light 
  • Air exchange

Intrinsic Factors:

  • Nutrient
  • Particle size of the substrate
  • Moisture
  • pH
  • Electrical conductivity
  • O2  

This ensures practically zero human intervention, leading to optimum   sterile conditions to prevent contamination from microorganisms.

State-Of-Art Quality Control

Quality is not an act. It’s a habit. Vanya’s  biotech division of Cordyceps Militaris production unit is accredited with ISO 9001-2015. ISO 22000, followed by HACCP, GMP & USDA Organic certifications are under way sequentially, as Quality Management System is an on-going exercise and never ending. 

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